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That includes more than 49,000 people who die from the effects of secondhand smoke

In a market-based economy, permissionless innovation allows entrepreneurs to create new products and to test those products in the marketplace.[61] If entrepreneurs think consumers want to buy something that is profitable for them to make, they ramp up production and sell their products

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First, data were derived from a select number of LMICs where the global burden of tobacco use is the highest and our findings may not generalize to other LMICs, particularly in under-represented regions like Africa

It is also present in smaller amounts in nightshades