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Pober JS, Min W (2006) Endothelial cell dysfunction, injury and death

Chong RLK, Chan ASE, Chua CMS, Lai YF

Studies show that combining vitamin C with vitamin E or other antioxidants can help reduce redness and speed recovery

Although research on lactylation inhibitors is still in its early stages, potential therapeutic strategies include targeting lactate metabolism, inhibiting lactylation-associated enzymes, or developing combination therapies that enhance existing treatment responses [39]

Furthermore, BTZ treatment in rats caused a decrease in SIRT1 levels, which subsequently reduced STAT3-mediated histone hyperacetylation in the neutrophilic alkaline phosphatase 1 promoter region of dorsal horn neurons, ultimately contributing to the development of mechanical pain hypersensitivity ( 3.6 Central nervous system dysfunction BTZ does not cross the blood-brain barrier, suggesting that it may indirectly contribute to CNS dysfunction (Meregalli et al., 2014)