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A prenatal vitamin should include B12, but since it is a key nutrient during pregnancy (contributing to fetal development, among other things), pregnant women who are vegan or have another reason to suspect a deficiency should talk to their doctor

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These dysfunctions may arise from impaired pyruvate dehydrogenase (PDH) function identified in muscle cells (390) and serum (184), as well as reduced plasma coenzyme Q10 (CoQ10) levels in ME/CFS blood and plasma (372, 391) that is inversely associated with fatigue severity (391)