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(20) reported that both tissue and serum levels of PON1 were significantly lower in patients with AA compared to controls, indicating a reduced capacity for antioxidant defense in these patients

This in turn alters downstream testosterone, estradiol, and progesterone levels, which impact ovulation timing and sperm production

Pretreatment with 10 g/g GHK-Cu significantly reduced the phosphorylation of both NF-B p65 and p38 MAPK, and slightly decreased JNK1/2 phosphorylation, with no effect on ERK1/2

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