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Found endogenously in human plasma (~200 ng/mL at age 20), saliva, and urine, GHK-Cu forms a high-affinity complex with copper(II) ions through its histidine imidazole nitrogen and peptide backbone coordination

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However, in the initial stages, the patients symptoms are not obvious, which can delay patient evaluation and diagnosis

The loss of his father was a shock to the family, but Graf stayed the course and enrolled at Louisiana State University (LSU) in Baton Rouge