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Dos: Rotate injection sites between the abdomen and upper thigh Clean the area thoroughly before injection Donts: Wear tight clothing around the injection site **If pain persists, consider taking an over-the-counter pain reliever like acetaminophen.** When to Contact Your Doctor or Pharmacist While these side effects are common, they should not be debilitating

Some people feel a slight reduction in appetite

Diabetes Care, 44(Supplement 1), S111S124

Muller DRP, Stenvers DJ, Malekzadeh A, et al

Additionally, unlike oral semaglutide, which is a peptide drug, Orforglipron belongs to a category of medications called small-molecule drugs