With respect to liver injury, steatohepatitis, fibrosis, and cirrhosis, liver cells are more susceptible to ferroptosis
Studies have demonstrated its ability to activate AMPK, regulate the folate-methionine cycle, and improve insulin sensitivity
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For the luciferase assay, HEK293T cells were seeded in 24-well plates until they reached 70% confluency and, subsequently, allocated into five groups: (1) transfected with GL-vector and Flag, (2) transfected with GL-VEGFA-WT and Flag-STAT6, (3) transfected with GL-VEGFA-Mut and Flag-STAT6, (4) transfected with GL-IL8-WT and Flag-STAT6, and (5) transfected with GL-IL8-Mut and Flag-STAT6