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For all tests, twosided p values less than 0.05 were considered statistically significant

Hypoglycaemia risk exists with both compoundsIGF-1 LR3 carries particular concern for hypoglycaemic episodes through unopposed IGF-1 receptor activation on muscle and peripheral tissues, which increase glucose uptake without coordinated hepatic glucose production adjustment

The key difference was that exendin-4 remained active in the body far longer than its human counterpart

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These risk factors can be broadly classified into demographic, metabolic, pharmacologic, and lifestyle factors