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In summary, our study establishes that VRK2 expression dictates PC cell vulnerability to GSH-targeted therapies through distinct mechanisms

Ingredients Rice flour, S-acetyl-glutathione, coating agent hydroxypropylmethylcellulose Important information: Food supplements must not be used as a substitute for a balanced, varied diet and a healthy lifestyle

Protein kinase A activity and anchoring are required for ovarian cancer cell migration and invasion

To investigate whether the increased GSH level at 100 g/ml 5-FOA (Figure S2A) was stable during longer-term cultivation of the modified strain, cellular GSH content was monitored every 10 generations during sequential batch cultivation in flasks at 100 g/ml 5-FOA (after every ~ 10 generations, aliquots of overnight culture were transferred to fresh medium giving OD 0.01 and re-incubated)