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This intervention activated mitophagy, enhanced tyrosine hydroxylase (TH) expression in the substantia nigra, and ultimately improved motor dysfunction in MPTP-induced PD mice

Thus, our cellular analyses provide evidence that the DNA binding activity of PDS5B is important for HR, DNA damage repair, and the maintenance of genome stability

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In aggregate, results from these initial experiments demonstrated that carnitine supplementation effectively improved insulin-stimulated glucose disposal in three distinct rodent models of insulin resistance

In fact, ALCAR is usually the preferred form in supplements for brain and nervous system support because it enters the brain quickly and is metabolized in mitochondria to L-carnitine, while its acetyl group is transferred to CoA to form acetyl-CoA