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Explaining that retatrutide works through triple agonist activation of GIP, GLP-1, and glucagon receptors, producing complementary effects on appetite, gastric emptying, insulin secretion, and energy expenditure doesnt fit in a TikTok caption

Duration of symptoms : If gastrointestinal symptoms persist beyond the initial titration period of Wegovy (typically up to 16 weeks), this may indicate poor tolerance rather than transient side effects

It mimics the natural hormone GLP-1, which regulates appetite, slows digestion, and helps control blood sugar levels

Weight loss typically follows a pattern: a modest initial drop (often partially water weight), followed by steady fat loss of 1 to 2 pounds per week at therapeutic doses

Prescribing it solely for inflammatory conditions would constitute off-label use and is not supported by current MHRA approvals or NICE guidance