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Formulary approaches may drive utilization of one or the other drug, both of which offer strong weight loss potential Employees should continue to monitor this class of medications as there are additional products in the pipeline, including oral semaglutide for obesity, expected to be FDA approved by the end of 2025

In essence, while no formal suggested gap is universal, practical considerations based on pharmacokinetic profiles point towards a 2-to-4-week washout period after a high dose of Tirzepatide before initiating a retatrutide dosage schedule after high dose of tirzepatide

Mounjaro works by activating both GLP-1 and GIP receptors, slowing digestion, reducing appetite, and improving blood sugar regulation, mechanisms that together support meaningful, evidence-based weight loss