Marso S
Regarding the GLP1-ra pharmacodynamics, a hypothesised mechanism through which GLP1-ra predisposes to diabetic retinopathy is via rapid reduction in HbA 1c which can lead to alterations in VEGF and IGF-1 that can lead to the development or early worsening of diabetic retinopathy [41, 42]
Coupled with that, GLP-1s are only covered for certain uses by most insurance companies, such as for managing diabetes, sleep apnea, and sometimes preventative care for overweight patients
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[DOI] [PubMed] [Google Scholar] 546.Jhala U.S., Canettieri G., Screaton R.A., Kulkarni R.N., Krajewski S., Reed J