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3, significant superiority in primary CV outcome was observed in three CVOTs using GLP-1 RAs (liraglutide OD in LEADER [56], dulaglutide OW in REWIND [36], and semaglutide OW in SUSTAIN 6 [non-inferiority and superiority were demonstrated in SUSTAIN 6 and pre-specified sensitivity analyses, respectively] [37])

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