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elevated GH (and downstream IGF1) supports tissue repair, immune function, and the restorative functions of stage3 NREM sleep

However, the ROS production is elevated in adipocytes with fat overload ( 4.1 Obesity-induced metabolic dysregulation and OS Excessive adipose tissue accumulation in individuals with obesity leads to a significant increase in plasma free fatty acid (FFA) levels ( 2 - ), thereby inducing OS ( Palmitic acid (PA), the most abundant saturated fatty acid in humans accounting for 20-30% of total fatty acids and widely present in diets ( Figure 2a

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