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In beta cell mitochondria, ROS produced during oxidative phosphorylation are detoxified by the glutathione redox system, which requires NADPH to maintain its redox state [92]

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Additionally, the combined expression of IL-17A, IL-17F, IL-21, retinoic acid receptor-related orphan receptor C (RORC), and transforming growth factor (TGF)- mRNA significantly predicted the rachmilewitz endoscopic index (REI), with IL-17A and IL-17F being associated with increased and decreased REI, respectively [67]

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