The diagram emphasizes feedback loops whereby ROS and cytokines amplify transporter inhibition and mitochondrial injury, consistent with experimental and clinical evidence
Moreover, ACTL6A overexpression relieved the inhibited GC cell proliferation caused by ACTL6A expression knockdown (Supplementary Fig 1c, d)
doi:10.1016/j.explore.2021.09.006 Originally published in 2021, this article has been revised and updated for accuracy and thoroughness.
Glutathione metabolism in type 2 diabetes and its relationship with microvascular complications and glycemia. PloS one vol
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