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J Physiol (2014) 592(10):218396.10.1113/jphysiol.2013.268771 143 IgawaHTakahashiMKakegawaKKinaAIkomaMAidaJet alMelanin-concentrating hormone receptor 1 antagonists lacking an aliphatic amine: synthesis and structure-activity relationships of novel 1-(Imidazo[1,2-a]pyridin-6-yl)pyridin-2(1H)-one derivatives
demonstrated that after IV administration, most GSH was immediately oxidized and disappeared from the circulation with a half-life of 10 minutes
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