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A 2024 study in Translational Psychiatry used positron emission tomography (PET) imaging to measure dopamine transporter binding in the striatum of adults with obesity before and after 12 weeks of semaglutide treatment

Even pulling the needle out too slowly or at an angle may disturb nearby tissue and capillaries

The net effect is simple: After weight loss, people are hungrier, feel less satisfied after eating and burn fewer calories than expected

This is a tolerability dose, not a therapeutic dose

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