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Statistical significance between pairs of groups was assessed using an unpaired two-sided t-test, one-way ANOVA followed by the Dunnett multiple comparison test, or two-way ANOVA with the Tukey multiple comparison test, as indicated

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A few users with both gut and musculoskeletal goals choose to use both routes in parallel oral for the digestive tract and injection for systemic targets

However, the data presented here clearly demonstrate that in isolated human islets, tirzepatide requires the GIPR to stimulate both insulin and glucagon secretion

Although liver biopsy is not routinely required, it may be useful in diagnostically uncertain cases