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Encouraging a culture of reporting among both patients and clinicians is essential to ensuring that medicines, including novel agents such as retatrutide, are used as safely as possible

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Significant ( p 0.05)

However, clinicians should maintain a broad differential diagnosis, as symptoms such as fatigue and reduced libido can result from multiple causes, including inadequate caloric intake, nutrient deficiencies (particularly vitamin D, iron, or B vitamins), sleep disturbances, depression, or other medical conditions

10.1038/nrneurol.2014.184 Nat