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The focus shifts from adjustment to consistency, and maintainable progress becomes the rhythm

A key aspect of this crosstalk is the livers secretion of hepatokines, such as fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (GDF15), which increase insulin sensitivity, 191 promote mitochondrial integrity in cardiomyocytes via the AMPK/FOXO3/SIRT3 signaling axis, 192 and suppress renal fibrosis

Enhancing neurogenesis and cognitive function, protecting against neurodegenerative disease and other age-related impairment

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van EenigeRYingZTramperNWiebingVSirajZde BoerJFet alCombined glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-1 receptor agonism attenuates atherosclerosis severity in APOE*3-Leiden.CETP mice