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Through the electrophile response element (EpRE), ERK1/2 and p38MAPK signaling pathways actively contribute to upregulation of GGT promoter 5 (GP5) activity in response to 4-hydroxynonenal (HNE) (43)

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As she recounted later on Instagram, On Jan

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10.1172/JCI40671 Pubmed Abstract CrossRef Google Scholar View reference in article 47

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Non-drug options like spinal cord stimulators can be considered if other treatments arent effective

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