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In addition to the conditions mentioned above, several risk factors increase the likelihood of B12 deficiency: Smoking Alcohol abuse Endocrine-related autoimmune disorders (such as diabetes or thyroid disorders) Gastrointestinal disorders like Crohns disease History of gastric bypass surgery or other stomach-altering surgeries Optimize Your Health
A 2025 meta-analysis of 16 studies involving 6,098 participants found no statistically significant difference between intramuscular, oral, and sublingual B12 supplementation routes
You can of course complain to you MP and ask for help, some will oblige, others will direct you to NICE or NHS England
The frustration is real, and the science is finally catching up to it
However, no clinical trials have evaluated this combination, and any multi-peptide or peptide-plus-GLP-1 protocol should be managed by a practitioner who can monitor labs, adjust doses, and watch for unexpected interactions
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