Balancing Benefits and Risks When weighing the decision to start or continue GLP-1 therapy, consider: The Benefits Weight loss: Average 1525% of body weight depending on the drug
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10.1093/toxsci/kfj111 [DOI] [PubMed] [Google Scholar] Klicek R., Kolenc D., Suran J., Drmic D., Brcic L., Aralica G., et al
Similar weight loss potential when combined with GLP-1
At present, several oral antidiabetic medications are used for the treatment of T2DM including, -glucosidases inhibitors, biguanides, sulfonylureas, meglitinides, GLP-1 receptor agonists (GLP-1RAs), peroxisome proliferator-activated receptor (PPAR-) agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors, and sodiumglucose transporter 2 (SGLT2) inhibitors