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This effect is probably a consequence of the increased baseline expression of caspase-1 and perhaps other inflammasome-associated factors, such as Gasdermins C2 and C3 that can act as terminal effectors of inflammatory cell lysis 27 , which were observed here in vitro and were previously described in ex vivo proteomics studies of mouse urothelia 8

Mild TBI as defined by the Veterans Affairs/Department of Defense Clinical Practice Guidelines, is classified as structural or physiological disruption of brain function resulting from an external traumatic force

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