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In addition, there is evidence that pioglitazone reduces the risk of MI and acute coronary syndrome in patients with cardiovascular diseases (CVD) and patients with type 2 diabetes who had previous myocardial infarction [220,221,222]

Hinman A, Holst CR, Latham JC, Bruegger JJ, Ulas G, McCusker KP

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The increase may be 5 to 15 times the normal value

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