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2024Continued treatment with tirzepatide for maintenance of weight reduction in adults with obesity: the surmount-4 randomized clinical trial

First, a mixture of RHEB and liposomes (200 nm) was incubated at 4 C overnight in lipid buffer at concentrations of 8 M and 1.8 mM, respectively

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doi: 10.1007/978-1-0716-3044-0_11 41 NunesM

Both medications are glucagon-like peptide-1 (GLP-1) receptor agonists, though tirzepatide also activates GIP receptors, which may contribute to slightly stronger average weight loss results in clinical trials