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Wegovy commonly causes nausea, vomiting, diarrhoea, constipation, and abdominal discomfort, particularly during the initial titration phase

(2017) have demonstrated that blockade of selective COX-1 or COX-2 enzymes or non-selective COX-inhibitor indomethacin, reversed most of the therapeutic effects of nesfatin-1 peptide on acetic acid-induced gastric ulcer, while COX-2-blockade was consistently more effective

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9,10 One of these studies evaluated a small cohort of semaglutide users undergoing endoscopy and found that 24% had residual gastric contents present on exam versus 5% in the non-semaglutide cohort nearly quintupling the incidence

Si bien algunos profesionales lo recetan en casos especficos como ayuda para bajar de peso, ese uso se considera off-label, es decir, fuera de las indicaciones oficiales autorizadas