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People do want to have some expression, Reszko says

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Gastrointestinal Effects The most frequently reported adverse reactions with semaglutide include: Nausea (occurring in 15-44% of patients depending on dose and indication) Vomiting (5-24% of patients) Diarrhea (8-30% of patients) Constipation (11-24% of patients) Abdominal pain (5-20% of patients) These symptoms typically emerge during dose escalation and often improve over time