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8 To date, all these peptides have followed similar trajectories: promising animal data with no evidence of efficacy in humans, despite extensive advertising and widespread availability of these compounds to athletes

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However, since IL-6 can cross the blood-brain barrier [67], the significant IL-6 sera levels determined at the first visit of ALS patients might have been abrogated at the second visit due to infiltration of this protein per se in addition to extravasation of inflammatory cells into the CNS parenchyma

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rhamnosus and 10^5 CFU/mL for L