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As such, the technique is often combined with or centrifugation forgone in favor of, the addition of an IGFBP blocking agent. IGF-2 has proved useful in this regard, being added in excess to samples to reduce interference from residual IGFBPs but methods are not consistent across different IGF-1 assays [112]

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We review insights from clinical trials, practical dosing schedules, and the most frequently asked research-use questions so you understand exactly how retatrutide is used in a research context