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Macrophages are classified as either traditionally activated (M1-type) or alternatively activated (M2-type), which have opposing roles in inflammation (Van den Bossche et al., 2016)

Since IGF-1R inhibition results in suppression of downstream AKT activation, the IGF-1R inhibitors (BMS-754807 and GSK1838705A) efficiently inhibit AKT phosphorylation, indicating that the drugs function properly

Hv1 inhibition rescues AD pathology by restoring microglial mitochondrial function and enhancing mitochondrial transfer

Ketogenic nutritional therapy (KeNuT)a multi-step dietary model with meal replacements for the management of obesity and its related metabolic disorders: a consensus statement from the working group of the Club of the Italian Society of Endocrinology (SIE)diet therapies in endocrinology and metabolism