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Large clinical trials have not consistently shown that isolated antioxidant supplements prevent cardiovascular disease in generally well-nourished populations

Those with a history of severe allergies While allergic reactions are rare, people with past reactions to IV treatments, medications, or supplements may face a higher risk

In biological systems, ascorbic acid can be found only at low pH, but in solutions above pH 5 it is predominantly found in the ionized form, ascorbate

Do not exceed the recommended maximum daily dose

That can mean more frequent colds, longer recovery times, recurring infections, and even an increased susceptibility to inflammatory or autoimmune conditions