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5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule research compound and a selective inhibitor of nicotinamide N-methyltransferase (NNMT)

In addition, in research on aging-related muscle atrophy (sarcopenia), it can promote muscle cell proliferation and differentiation, reduce muscle cell apoptosis, and enhance muscle strength and endurance by activating the SIRT1 signaling pathway

If you take metformin for diabetes or use proton pump inhibitors for acid reflux, your doctor might recommend monitoring your B12 status

Atrophic gastritis Atrophic gastritis is thought to affect 10%-30% of people over 60 years of age (7)

A patient info leaflet advises women to tell clinicians if pregnant, but also notes supplementing prevents deficiency risks