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However, other options exist: Medicare patients: Check if your Part D plan covers Zepbound, or explore Lilly's Patient Assistance Program No insurance: Consider LillyDirect ($299-$449/month for self-pay vials) State Restrictions Savings card benefits may be limited in certain states: Massachusetts: Card not valid if an AB-rated generic equivalent is available California: Card not valid if an FDA-approved therapeutic equivalent is available Currently, there is no generic equivalent for Zepbound (tirzepatide), so these restrictions don't apply