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Mol Pharmacol 80:210218 [DOI] [PMC free article] [PubMed] [Google Scholar] Quillinan N, Lau EK, Virk M, von Zastrow M, Williams JT

Patients often discover it later

Although corticosteroids and biologics have shown clinical benefits, their long-term use is often constrained by high costs, adverse effects, heterogeneous patient responses, and limited applicability across AD subtypes

These signal within the brain and nervous system to influence things such as mood, appetite and pain growth factors (IGF-1)

It aids in detoxification pathways (e.g., glutathione regeneration) and counters oxidative stress induced by substance use