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The published human evidence is thin and does not yet confirm it: in a small controlled study of healthy elderly men with low baseline IGF-1, six weeks of nightly GHRH injections increased nocturnal growth hormone release and improved two of six muscle-strength measures, but produced no measurable change in weight, waist-to-hip ratio, or DEXA-assessed fat and muscle mass (7)

In my practice, Ive seen clients who, after losing weight on Ozempic, express concerns about feeling weaker or noticing changes in their bodys appearance