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PT-141# PT-141 was derived from MT-2 through a single structural modification: the C-terminal amide group of MT-2 (-NH2) was converted to a free acid (-OH)

The purpose of this study is to compare the risk of all-cause death and cardiovascular outcomes, including heart failure, in patients with type 2 diabetes treated with semaglutide versus dulaglutide in a real-world setting using TriNetX, a global healthcare data and analytics platform

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Publication bias of the included studies suggested a large symmetry whose interpretation is inherently limited due to the small number of studies and was assessed using funnel plots, highlighting the need for the implementation of other formal statistical tests for funnel plot asymmetry, such as Eggers test or Beggs test