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The formulation also provides antifibrotic benefits, helping to prevent excessive fibroblast proliferation and scar formation

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Both D1- and D2-like receptors can also activate the phosphatidylinositol 3-kinase/Akt signaling cascade, although the immunologic impact of dopamine-mediated activation of this pathway is not well understood (Zhen et al., 2001

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Overall, the low-FODMAP diet remains the core intervention, and probiotics may offer an additional benefit in modulating stool form, though this requires validation in larger trials with long-term follow-up