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doi: 10.1186/s12964-024-01871-9 58 LiP.YuJ.HuangF.ZhuY.-Y.ChenD.-D.ZhangZ.-X.et al

In certain cases, clinically confirmed low testosterone may be associated with a condition known as hypogonadism, which occurs when the body does not produce adequate levels of sex hormones

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While these medications don't directly impair fertility, they can actually improve conception potential through metabolic optimizationparticularly in individuals with obesity-related reproductive dysfunction

It is known that mTORC2 phosphorylates Akt and appears to regulate mainly cell proliferation and cell survival [110] (Figure 4) The effect growth factors have on mTORC1 is mediated through phosphatidylinositol-3,4,5-triphosphate kinase (PI3K) activation, the subsequent activation of phosphoinositide-dependent kinase (PDK1) and Akt