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Description

J Biol Chem 270:1567515685

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How Lipo B and Tirzepatide Work Through Different Pathways Tirzepatide activates both GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors with high affinity

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Inflammation Chronic inflammation is a key driver of metabolic dysfunction in obesity, with adipose tissue secreting cytokines like TNF-, IL-6 and IL-1 that disrupt insulin signaling and fuel disease progression

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