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The delay of gastric emptying with semaglutide may influence the absorption of concomitantly administered oral medications [see Drug Interactions (7.2)]

It effects for weight loss have been modest compared to Wegovy (5 to 8 pounds for the 7 and 14 mg dose, respectively)

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Importance of Gradual Dosage Increase The rationale behind starting with a sub-therapeutic dose during the initial weeks is to allow your body to adapt to the medication and minimize gastrointestinal side effects