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Zepbound / tirzepatide FDA-approved since November 2023

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This patient developed aspiration pneumonia requiring intensive care unit ventilation, highlighting that effects may persist beyond expected pharmacological half-lives [5]

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Concurrent activation of the GIP receptor appears to augment insulinotropic effects and may improve adipose tissue metabolism while attenuating some of the gastrointestinal adverse effects commonly associated with GLP 1 receptor agonists

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