A qualified nurse or doctor reviews your medical history, your diet, any current medication and any GP-confirmed B12 deficiency
Each batch is synthesized using Solid-Phase Peptide Synthesis (SPPS) under tightly controlled conditions to ensure molecular precision, purity, and reproducibility
The most common concentrations include 2.5mg/mL (typically in smaller 1 mL vials containing 2.5 mg total), 5mg/mL (in 1 mL vials containing 5 mg total or 2 mL vials containing 10 mg total), and occasionally higher concentrations for patients on maintenance doses
In both Cagri- and rAmy-bound AMY 1 R structures, F83 RAMP1 packs over R126 ECD stabilising the same interface of the RAMP1-CTR ECD when bound by both peptides 15
Antibodies to intrinsic factor (IF) bind to IF and prevent formation of the IF-B 12 complex, further inhibiting vitamin B 12 absorption