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Kobayashi, A., Masumura, Y., and Yamazaki, N

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Medical Weight Loss Overview If youre struggling with: Weight gain despite diet and exercise Constant hunger or cravings Slow metabolism or insulin resistance GLP-1 medications help regulate appetite, reduce cravings, and support consistent, sustainable weight loss

The SELECT cardiovascular outcomes trial (N=17,604), published in NEJM 2023 (DOI: 10.1056/NEJMoa2307563), demonstrated a 20% reduction in major adverse cardiovascular events (MACE) -- the composite of cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke -- in overweight or obese adults without diabetes

These medicines exert direct and indirect effects on the brain, improving neuronal health and thereby impacting a range of central nervous system disorders, including stroke, substance use disorders, Parkinsons disease, and Alzheimers disease