Neuroprotection and brain injury repair&Research on metabolic disease models Cerebral ischemia model: After occlusion of the middle cerebral artery (MCAO) in rats, injection of IGF-1 LR3 (10 g/kg) into the lateral ventricle can: Reduce the area of neuronal death by 30%
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Only 4.2% of participants discontinued due to side effects after week 24, indicating excellent long-term tolerability
10.1016/j.neuroscience.2013.12.024 155 WilkinsonK
and C10:1, C14:1, C16:1, C18:1, and C18:2) and urinary organic acids (increased urinary excretion of ethylmalonic, adipic, suberic, glutaric and methylsuccinic acids, hexanoylglycine, and tiglylglycine) [3]