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Due to the high demand of glutamine, this amino acid is also used for imaging based on 18F-labeled glutamine tracers in preclinical and clinical studies, especially when the use of 18F-FDG is not feasible, like in the brain [15,16]

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394 In certain regions, a precautionary measure involves tailoring the allopurinol dosage based on creatinine clearance, aiming to mitigate the risk associated with SCARs, particularly considering renal failure as a predisposing factor for these adverse reactions

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