GLP-1 receptors exist throughout the vascular system, and their activation may alter autoregulation of blood flow to the optic nerve head, particularly during nocturnal blood pressure dips when many NAION events occur
Treatment continuation requires demonstration of adequate response: For liraglutide: at least 5% weight loss after 12 weeks at the maintenance dose of 3.0 mg For semaglutide: assessment after approximately 3 months at the maintenance dose of 2.4 mg, with discontinuation if less than 5% weight loss achieved Private prescribing is available but costs vary by provider and medication
Also, be sure to inform your healthcare provider of all prescription, over-the-counter, and herbal medications that you are taking in order to avoid any drug interactions
Assessment and history A structured history should aim to distinguish (a) true vaginal mucosal symptoms, (b) vulvar dermatologic disease, (c) urinary tract symptoms, and (d) sexual function/arousal issues
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