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The foregoing Examples are provided in order to illustrate various embodiments of the invention, but should not be inteipreted as limiting the invention in any way

the clinical relevance of this finding in humans is unknown, and in UK and EU prescribing information this is noted as a precaution rather than a formal contraindication but individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2) should discuss this with their doctor